Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7268455 | 0.85 | HPGD (0.48) | KDM4EALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9524342 | 0.83 | HTT (0.43) | MAOBKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL7859572 | 0.81 | MAPT (0.59) | MAOBALDH1A1MAPTPOLBLMNA | |
| Bicarbonate SCHEMBL11298239 | 0.75 | KDM4E (0.60) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL10581498 | 0.74 | ALDH1A1 (0.49) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL29009279 | 0.73 | ALDH1A1 (0.53) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL11853555 | 0.72 | ALDH1A1 (0.40) | ALDH1A1KMT2AMAPTPOLBLMNA | |
| SCHEMBL8645685 | 0.71 | ALDH1A1 (0.54) | MAOBKDM4EALDH1A1KMT2APOLB | |
| SCHEMBL13034049 | 0.71 | ALDH1A1 (0.54) | MAOBALDH1A1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL7332635 | 0.71 | ADORA2A (0.41) | MAOBKDM4EALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743574-B1 | Migration imaging members | XEROX CORP (US) | 2000-12-27 | — | — | EP | claimed |
| EP-0743573-B1 | Method for obtaining image contrast migration imaging members | XEROX CORP (US) | 2000-09-06 | — | — | EP | claimed |
| EP-0743573-A2 | Method for obtaining image contrast migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| EP-0743574-A2 | Migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| US-5563014-A | SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT | XEROX CORPORATION (US) | 1996-10-08 | — | — | US | claimed |
| US-5514505-A | SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE | XEROX CORPORATION (US) | 1996-05-07 | — | — | US | claimed |
| US-8481696-B2 | Glycosylated glycopeptide antibiotic derivatives | SHIONOGI & CO., LTD. (JP) | 2013-07-09 | — | — | US | disclosed |
| US-8481696-B2 | Glycosylated glycopeptide antibiotic derivatives | SHIONOGI & CO., LTD. (JP) | 2013-07-09 | — | — | US | disclosed |
| US-20100286364-A1 | GLYCOSYLATED GLYCOPEPTIDE ANTIBIOTIC DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2010-11-11 | — | — | US | disclosed |
| US-20100286364-A1 | GLYCOSYLATED GLYCOPEPTIDE ANTIBIOTIC DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2010-11-11 | — | — | US | disclosed |
| US-20070161581-A1 | Novel aminoglycoside antibiotics effective against methicillin resistant staphylococcus auerus (mrsas) | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-07-12 | — | — | US | disclosed |
| EP-1710248-A1 | NOVEL AMINOGLYCOSIDE ANTIBIOTIC EFFECTIVE AGAINST METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS (MRSA) | MEIJI SEIKA KAISHA LTD. (JP) | 2006-10-11 | — | — | EP | disclosed |
| US-6583144-B2 | Piperazine substituted isoquinoline, 1,3-benzoxazine, or 1,3-benzothiazine derivatives; inhibitors against the biosynthesis of triglycerides and secretion of apolipoprotein b and treatment of hyperlipidemia | MEIJI SEIKA KAISHA, LTD. (JP) | 2003-06-24 | — | — | US | disclosed |
| EP-0126587-A1 | Carboxylic thio-pyrrolidinyl beta-lactam compounds and production thereof | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1984-11-28 | — | — | EP | disclosed |
| EP-0096392-A1 | Novel aminoglycosides, process for production thereof and use thereof | KOWA COMPANY, LTD. (JP) | 1983-12-21 | — | — | EP | disclosed |
| EP-0094625-A1 | Novel aminoglycosides and process for production thereof | KOWA COMPANY, LTD. (JP) | 1983-11-23 | — | — | EP | disclosed |
| US-4337335-A | Transition metal salt complexes of polyamino organic compounds | SCHERING CORPORATION (US) | 1982-06-29 | — | — | US | disclosed |
| US-4296242-A | Process for the preparation of chiral 3-amino-2-hydroxypropionic acid and N-blocked derivatives thereof | SCHERING CORPORATION (US) | 1981-10-20 | — | — | US | disclosed |
| US-4230847-A | Aminoglycoside antibiotic compounds | SCHERING CORPORATION (US) | 1980-10-28 | — | — | US | disclosed |
| US-4180565-A | ANTIBACTERIAL AGENTS, ANTIBIOTICS | SCHERING CORPORATION (US) | 1979-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161581-A1 | Novel aminoglycoside antibiotics effective against methicillin resistant staphylococcus auerus (mrsas) | RPS11, RPS18, MRPS17 | MAOB 3092/4885KDM4E 4656/4885ALDH1A1 2089/4885 |
| US-20100286364-A1 | GLYCOSYLATED GLYCOPEPTIDE ANTIBIOTIC DERIVATIVES | CSGALNACT1, OGT, GALNT1 | MAOB 4506/4885KDM4E 2334/4885ALDH1A1 724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.