Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | DUT | P33316 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | VDR | P11473 | 1/20 | 0.38 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TK1 | P04183 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27443036 | 1.00 | TK2 (0.47) | TK2ALDH1A1KIF11DUTCA12 | |
| SCHEMBL27443043 | 1.00 | TK2 (0.47) | TK2ALDH1A1KIF11DUTCA12 | |
| SCHEMBL20958136 | 1.00 | TK2 (0.47) | TK2ALDH1A1KIF11DUTCA12 | |
| SCHEMBL9523426 | 1.00 | TK2 (0.47) | TK2ALDH1A1KIF11DUTCA12 | |
| SCHEMBL4303777 | 0.94 | TK1 (0.43) | TK2ALDH1A1KIF11DUTCA12 | |
| SCHEMBL4013278 | 0.94 | TK2 (0.42) | TK2ALDH1A1KIF11DUTCA12 | |
| SCHEMBL2381255 | 0.92 | SLC6A11 (0.43) | TK2ALDH1A1KIF11CA12CA1 | |
| SCHEMBL6046754 | 0.92 | SLC6A11 (0.43) | TK2ALDH1A1KIF11CA12CA1 | |
| SCHEMBL31516447 | 0.88 | TK1 (0.46) | TK2ALDH1A1KIF11VDRCYP24A1 | |
| SCHEMBL26103993 | 0.86 | TK2 (0.47) | TK2ALDH1A1KIF11VDRCYP24A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540612-A1 | HETEROBIFUNCTIONAL REAGENTS AND CONJUGATES WITH OXAALKYLENE UNITS FOR AMPHIPHILIC BRIDGE STRUCTURES | Pharmacia AB (SE) | 1993-05-12 | — | — | EP | disclosed |
| WO-1992001474-A1 | HETEROBIFUNCTIONAL REAGENTS AND CONJUGATES WITH OXAALKYLENE UNITS FOR AMPHIPHILIC BRIDGE STRUCTURES | KABI PHARMACIA AB (SE) | 1992-02-06 | — | — | WO | disclosed |