Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9525776 | 0.86 | ALDH1A1 (0.53) | ALDH1A1NPSR1KMT2AL3MBTL1MAPT | |
| SCHEMBL8011641 | 0.83 | ALDH1A1 (0.44) | ALDH1A1NPSR1KMT2AL3MBTL1MAPT | |
| SCHEMBL8011640 | 0.83 | ALDH1A1 (0.44) | ALDH1A1NPSR1KMT2AL3MBTL1MAPT | |
| SCHEMBL6950421 | 0.80 | PTGS2 (0.60) | ALDH1A1NPSR1KMT2AL3MBTL1MAPT | |
| SCHEMBL6950419 | 0.80 | PTGS2 (0.60) | ALDH1A1NPSR1KMT2AL3MBTL1MAPT | |
| SCHEMBL6949903 | 0.79 | ALDH1A1 (0.46) | ALDH1A1NPSR1KMT2AL3MBTL1MAPT | |
| SCHEMBL9023690 | 0.79 | ALDH1A1 (0.46) | ALDH1A1NPSR1KMT2AL3MBTL1MAPT | |
| SCHEMBL9727237 | 0.79 | KDM4E (0.45) | ALDH1A1KMT2AL3MBTL1MAPTGAA | |
| SCHEMBL9727241 | 0.79 | KDM4E (0.45) | ALDH1A1KMT2AL3MBTL1MAPTGAA | |
| SCHEMBL6949454 | 0.78 | GAA (0.50) | ALDH1A1KMT2AL3MBTL1MAPTMDM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274642-B1 | HERBICIDAL AND FUNGICIDAL AGENTS BASED ON SUBSTITUTED PYRAZOLIN-5-ONE DERIVATIVES | BAYER AG (DE) | 1993-08-11 | — | — | EP | claimed |
| US-5162528-A | Pre- and post-emergence; phytaphthora in tomato plants; rice and wheat | BAYER AKTIENGESELLSCHAFT (DE) | 1992-11-10 | — | — | US | claimed |
| EP-0274642-B1 | HERBICIDAL AND FUNGICIDAL AGENTS BASED ON SUBSTITUTED PYRAZOLIN-5-ONE DERIVATIVES | BAYER AG (DE) | 1993-08-11 | — | — | EP | disclosed |