Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 4/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19086336 | 0.79 | ATM (0.57) | KDM4EALDH1A1KMT2AATMPIM1 | |
| SCHEMBL10709427 | 0.71 | MET (0.48) | KDM4EALDH1A1KMT2AATMPIM1 | |
| SCHEMBL24913266 | 0.70 | ESR2 (0.46) | KDM4EALDH1A1IDO1GAAGALR3 | |
| SCHEMBL11449584 | 0.70 | MAPT (0.58) | KDM4EATMPIM1HPGDGLA | |
| SCHEMBL1162742 | 0.70 | PIM1 (0.54) | KDM4EALDH1A1RXFP1KMT2AIDO1 | |
| SCHEMBL9701346 | 0.69 | KDM4E (0.64) | KDM4EALDH1A1RXFP1KMT2AATM | |
| SCHEMBL2822668 | 0.66 | KDR (0.47) | ALDH1A1KMT2AATML3MBTL1MEN1 | |
| SCHEMBL6217613 | 0.65 | KDM4E (0.54) | KDM4EALDH1A1RXFP1KMT2APIM1 | |
| SCHEMBL5184144 | 0.65 | PIM1 (0.61) | KDM4EALDH1A1RXFP1KMT2APIM1 | |
| SCHEMBL11023464 | 0.65 | KDM4E (0.46) | KDM4EALDH1A1KMT2AATMPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550576-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |