Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | GAA | P10253 | 5/20 | 0.64 |
| ▸ | GLA | P06280 | 2/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701560 | 0.85 | KDM4E (0.59) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9702565 | 0.81 | KDM4E (0.55) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9700724 | 0.80 | KDM4E (0.66) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL7397061 | 0.78 | KDM4E (0.64) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9525290 | 0.78 | KDM4E (0.64) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL11735164 | 0.78 | KDM4E (0.64) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL11741908 | 0.78 | KDM4E (0.64) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9526447 | 0.78 | GAA (1.00) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9700710 | 0.78 | KDM4E (0.64) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL4474609 | 0.77 | MDM2 (0.62) | KDM4EALDH1A1GAAGLAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |