Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | CLPP | Q16740 | 2/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524496 | 1.00 | ALDH1A1 (0.46) | ALDH1A1MAPK1ITGB1ITGA4TAS1R3 | |
| SCHEMBL13923473 | 0.84 | ITGB1 (0.47) | ALDH1A1MAPK1ITGB1ITGA4TAS1R3 | |
| SCHEMBL16898779 | 0.83 | ALDH1A1 (0.44) | ALDH1A1MAPK1TAS1R3TAS1R1ALOX5 | |
| SCHEMBL18241389 | 0.83 | ALDH1A1 (0.44) | ALDH1A1MAPK1TAS1R3TAS1R1ALOX5 | |
| SCHEMBL16898289 | 0.80 | L3MBTL1 (0.55) | TAS1R3TAS1R1ALOX5CA12CA1 | |
| SCHEMBL16898288 | 0.80 | L3MBTL1 (0.55) | TAS1R3TAS1R1ALOX5CA12CA1 | |
| SCHEMBL8819401 | 0.80 | CA12 (0.43) | ALDH1A1MAPK1TAS1R3TAS1R1ALOX5 | |
| SCHEMBL8819411 | 0.80 | CA12 (0.43) | ALDH1A1MAPK1TAS1R3TAS1R1ALOX5 | |
| SCHEMBL10654280 | 0.78 | ALDH1A1 (0.49) | ALDH1A1HPGDFLT1FLT4KDR | |
| SCHEMBL10570037 | 0.78 | ITGB1 (0.55) | ITGB1ITGA4CA1CA2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0327190-B1 | Pyrido(2,3-d)pyrimidine derivatives | UNIV PRINCETON (US) | 1993-12-08 | — | — | EP | disclosed |
| EP-0327190-A1 | Pyrido(2,3-d)pyrimidine derivatives | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1989-08-09 | — | — | EP | disclosed |