Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 7/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31297525 | 0.85 | CA12 (0.51) | ABCG2CYP2C9KDM4ECYP3A4HSD17B10 | |
| SCHEMBL120954 | 0.85 | CA12 (0.51) | ABCG2CYP2C9KDM4ECYP3A4HSD17B10 | |
| SCHEMBL11300703 | 0.82 | ABCG2 (0.66) | ABCG2CYP2C9KDM4ECYP3A4HSD17B10 | |
| SCHEMBL253523 | 0.79 | ABCG2 (1.00) | ABCG2CYP2C9KDM4ECYP3A4HSD17B10 | |
| SCHEMBL29993383 | 0.79 | ABCG2 (1.00) | ABCG2CYP2C9KDM4ECYP3A4HSD17B10 | |
| SCHEMBL23883097 | 0.79 | CYP2C9 (0.63) | ABCG2CYP2C9KDM4ECYP3A4HSD17B10 | |
| SCHEMBL1001259 | 0.78 | ABCG2 (0.60) | ABCG2CYP2C9KDM4ECYP3A4HSD17B10 | |
| SCHEMBL4287358 | 0.78 | MAOA (0.59) | ABCG2CYP2C9KDM4ECYP3A4HSD17B10 | |
| SCHEMBL29690162 | 0.77 | CYP2C9 (0.50) | ABCG2CYP2C9KDM4ECYP3A4HSD17B10 | |
| SCHEMBL6466933 | 0.77 | ABCG2 (0.63) | ABCG2CYP2C9KDM4ECYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108883088-A | Using the Epithelial and stromal of chromone derivative conversion inhibitory activity as fibrosis prevention and the new application for the treatment of pharmaceutical composition | 欧斯特奥纽罗根有限公司 | 2018-11-23 | — | — | CN | claimed |
| CN-104098538-A | Synthetic method for 2-methyl-5,7-dimethoxychromone | TAICANG BOYI CHEMICAL CO LTD | 2014-10-15 | — | — | CN | claimed |
| US-20230321197-A1 | Polyphenolic Insulin | KIMBALL WESTWARD LLC (US) | 2023-10-12 | — | — | US | disclosed |
| CN-110305094-A | Two kinds of flavone compounds and its extraction separation method and purposes in purslane | 辽宁中医药大学 | 2019-10-08 | — | — | CN | disclosed |
| US-20160143878-A1 | ANTIBACTERIAL AGENT | JUNTENDO EDUCATIONAL FOUNDATION (JP) | 2016-05-26 | — | — | US | disclosed |
| US-20150322033-A1 | ANTIBACTERIAL AGENT | JUNTENDO EDUCATIONAL FOUNDATION (JP) | 2015-11-12 | — | — | US | disclosed |
| CN-104098538-A | Synthetic method for 2-methyl-5,7-dimethoxychromone | TAICANG BOYI CHEMICAL CO LTD | 2014-10-15 | — | — | CN | disclosed |
| CN-102382091-B | Method for synthesizing multi-substituted chromone compound | UNIV ZHEJIANG | 2014-07-09 | — | — | CN | disclosed |
| CN-1148593-A | Production method for chromone derivative and its medicinal composition | KUREHA CHEMICAL IND CO LTD (JP) | 1997-04-30 | — | — | CN | disclosed |
| EP-0241003-B1 | 4H-1-BENZOPYRAN-4-ONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-10-06 | — | — | EP | disclosed |
| US-4900727-A | ANTIALLERGENS, ANALGESICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-02-13 | — | — | US | disclosed |
| EP-0241003-A2 | 4H-1-benzopyran-4-one derivatives, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-10-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160143878-A1 | ANTIBACTERIAL AGENT | MRPL21, Q6ZSR9, NQO2 | ABCG2 272/4885CYP2C9 806/4885KDM4E 3210/4885 |
| US-20150322033-A1 | ANTIBACTERIAL AGENT | Q6ZSR9, MRPL21, NQO2 | ABCG2 278/4885CYP2C9 869/4885KDM4E 3156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.