Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 9/20 | 0.63 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.63 |
| ▸ | INCENP | Q9NQS7 | 3/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CTSA | P10619 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HK2 | P52789 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL402416 | 0.88 | CA12 (0.62) | SYKAURKBINCENPCTSAALDH1A1 | |
| SCHEMBL10296036 | 0.87 | MKNK1 (0.54) | SYKAURKBINCENPL3MBTL1AKR1C3 | |
| SCHEMBL35823 | 0.85 | PTGS2 (0.58) | SYKAURKBINCENPL3MBTL1MAPT | |
| SCHEMBL3205541 | 0.85 | LMNA (0.59) | LMNA | |
| SCHEMBL5991136 | 0.85 | MKNK1 (0.56) | SYKAURKBINCENPCTSAALDH1A1 | |
| SCHEMBL16712923 | 0.85 | LMNA (0.51) | SYKAURKBINCENPSMN1; SMN2CTSA | |
| SCHEMBL2787158 | 0.84 | SYK (0.51) | SYKAURKBINCENPL3MBTL1MAPT | |
| SCHEMBL12895860 | 0.83 | KMT2A (0.51) | SYKAURKBINCENPL3MBTL1MAPT | |
| SCHEMBL14241376 | 0.83 | SMN1; SMN2 (0.60) | SYKAURKBINCENPL3MBTL1MAPT | |
| SCHEMBL9473321 | 0.83 | SYK (0.66) | SYKAURKBINCENPMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550576-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |