Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.53 |
| ▸ | CA1 | P00915 | 7/20 | 0.53 |
| ▸ | CA9 | Q16790 | 7/20 | 0.53 |
| ▸ | CA7 | P43166 | 5/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDR | P35968 | 3/20 | 0.52 |
| ▸ | FLT1 | P17948 | 2/20 | 0.52 |
| ▸ | FLT4 | P35916 | 2/20 | 0.52 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.52 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9486556 | 0.84 | MEN1 (0.67) | CA2CA1CA9MEN1KMT2A | |
| SCHEMBL162962 | 0.84 | KDR (0.67) | CA2CA1CA9CA7MEN1 | |
| SCHEMBL9488026 | 0.82 | CNR2 (0.61) | CA2CA1CA9CNR2MEN1 | |
| SCHEMBL9569790 | 0.81 | IDH1 (0.48) | CA2CA1CA9CA7KDR | |
| SCHEMBL9486495 | 0.81 | CA12 (0.66) | CA2CA1CA9CA7MEN1 | |
| SCHEMBL4556067 | 0.81 | KDR (0.75) | CA2CA1CA9CA7MEN1 | |
| SCHEMBL9478768 | 0.81 | CA2 (0.44) | CA2CA1CA9CA7CNR2 | |
| SCHEMBL9478180 | 0.81 | CA2 (0.44) | CA2CA1CA9CA7CNR2 | |
| SCHEMBL8761299 | 0.80 | GFER (0.44) | CA2CA1CA9CA7MEN1 | |
| SCHEMBL11831657 | 0.78 | KDR (0.62) | CA2CA1CA9CA7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0166615-B1 | IMPROVEMENTS IN OR RELATING TO BENZENESULFONAMIDO DERIVATIVES | ELI LILLY AND COMPANY (US) | 1993-05-26 | — | — | EP | disclosed |