Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569776 | 0.88 | IDH1 (0.55) | IDH1MAOBMAOAEPHX1NPC1 | |
| SCHEMBL9569774 | 0.82 | ESR1 (0.52) | MAOBMAOACA1CA2CA9 | |
| SCHEMBL9524746 | 0.81 | CA2 (0.53) | CA1CA2CA7CA9EPHX1 | |
| SCHEMBL22803870 | 0.79 | ESR1 (0.57) | IDH1MAOBMAOATRPV1KDR | |
| SCHEMBL22803700 | 0.78 | MAOB (0.54) | IDH1MAOBMAOACA1CA2 | |
| SCHEMBL8761299 | 0.76 | GFER (0.44) | CA1CA2CA7CA9KDR | |
| SCHEMBL9478768 | 0.75 | CA2 (0.44) | CA1CA2CA7CA9TRPV1 | |
| SCHEMBL9478180 | 0.75 | CA2 (0.44) | CA1CA2CA7CA9TRPV1 | |
| SCHEMBL22803273 | 0.74 | IDH1 (0.53) | IDH1MAOBMAOAEPHX1NPC1 | |
| SCHEMBL13675794 | 0.74 | KDR (0.48) | MAOBMAOACA9KDRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560554-A2 | Antitumor compositions and methods of treatment | ELI LILLY AND COMPANY (US) | 1993-09-15 | — | — | EP | disclosed |
| US-5169860-A | Benzofuran or benzothiophene arylsulfonylureas | ELI LILLY AND COMPANY (US) | 1992-12-08 | — | — | US | disclosed |