Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9523084 | 0.92 | EGFR (0.43) | EGFRCRHR1RPS6KB1LMNABCL2 | |
| SCHEMBL9524309 | 0.89 | EGFR (0.43) | EGFRCRHR1RPS6KB1LMNABCL2 | |
| Oxalic Acid SCHEMBL9523891 | 0.87 | RPS6KB1 (0.45) | EGFRCRHR1RPS6KB1BCL2BCL2L1 | |
| SCHEMBL8756661 | 0.75 | EGFR (0.41) | EGFRCRHR1RPS6KB1LMNA | |
| SCHEMBL11287675 | 0.74 | EGFR (0.49) | EGFRCRHR1RPS6KB1LMNAP2RX3 | |
| SCHEMBL9523322 | 0.73 | TTBK1 (0.41) | EGFRCRHR1LMNAMCL1 | |
| SCHEMBL9084666 | 0.73 | PTGER4 (0.40) | EGFRCRHR1RPS6KB1BCL2BCL2L1 | |
| SCHEMBL9523823 | 0.72 | CRHR1 (0.42) | EGFRCRHR1RPS6KB1LMNA | |
| Hydrochloric Acid SCHEMBL9523871 | 0.72 | PTGER4 (0.39) | EGFRCRHR1RPS6KB1BCL2BCL2L1 | |
| SCHEMBL9523756 | 0.72 | CRHR1 (0.39) | EGFRCRHR1RPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0264217-B1 | ARALKYLAMINOPYRIMIDINE DERIVATIVE, PROCESS FOR PRODUCING THEREOF AND INSECTICIDE, ACARICIDE AND FUNGICIDE CONTAINING SAID DERIVATIVE AS ACTIVE INGREDIENT | UBE INDUSTRIES, LTD. (JP) | 1993-06-30 | — | — | EP | disclosed |
| US-4985426-A | AGRICULTURAL USE | UBE INDUSTRIES, LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| US-4895849-A | Aralkylaminopyrimidine compounds which are useful as for producing thereof and insecticides | UBE INDUSTRIES, LTD. (JP) | 1990-01-23 | — | — | US | disclosed |
| EP-0264217-A2 | Aralkylaminopyrimidine derivative, process for producing thereof and insecticide, acaricide and fungicide containing said derivative as active ingredient | UBE INDUSTRIES, LTD. (JP) | 1988-04-20 | — | — | EP | disclosed |