Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.49 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.39 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.39 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.39 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.39 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.39 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.39 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.39 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11281906 | 0.82 | EGFR (0.52) | EGFRRPS6KB1LMNAP2RX3CRHR1 | |
| SCHEMBL9403796 | 0.79 | EGFR (0.55) | EGFRRPS6KB1CRHR1AURKA | |
| SCHEMBL8024728 | 0.79 | EGFR (0.49) | EGFRRPS6KB1LMNAP2RX3CRHR1 | |
| SCHEMBL11105703 | 0.77 | EGFR (0.52) | EGFRRPS6KB1LMNAP2RX3CRHR1 | |
| SCHEMBL11105495 | 0.77 | EGFR (0.52) | EGFRRPS6KB1LMNAP2RX3CRHR1 | |
| SCHEMBL9524309 | 0.77 | EGFR (0.43) | EGFRRPS6KB1LMNAP2RX3CRHR1 | |
| SCHEMBL9215503 | 0.76 | EGFR (0.47) | EGFRRPS6KB1LMNACRHR1 | |
| SCHEMBL8303141 | 0.75 | EGFR (0.38) | EGFRRPS6KB1LMNAP2RX3CRHR1 | |
| SCHEMBL8756661 | 0.75 | EGFR (0.41) | EGFRRPS6KB1LMNACRHR1 | |
| SCHEMBL8755999 | 0.74 | TPH1 (0.39) | EGFRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057440-A1 | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY LIMITED (JP) | 1982-08-11 | — | — | EP | disclosed |