Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9525015 | 0.92 | TP53 (0.40) | MEN1KMT2AHSD17B10 | |
| SCHEMBL9525496 | 0.78 | MAPT (0.53) | MEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL9726988 | 0.77 | KMT2A (0.43) | MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL9524574 | 0.75 | MAPT (0.47) | MEN1KMT2APOLBALDH1A1HSD17B10 | |
| SCHEMBL9727194 | 0.73 | TP53 (0.46) | MEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL7869540 | 0.72 | MEN1 (0.46) | MEN1KMT2AHSD17B10 | |
| SCHEMBL9868470 | 0.72 | TP53 (0.40) | — | |
| SCHEMBL9524966 | 0.72 | TP53 (0.46) | MEN1KMT2AHSD17B10 | |
| SCHEMBL9524668 | 0.71 | HSD17B10 (0.55) | MEN1KMT2AHSD17B10 | |
| SCHEMBL9524861 | 0.71 | TP53 (0.39) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0466711-B1 | DIHYDROPYRIMIDINE ANTIALLERGY AGENTS | PFIZER LTD (GB) | 1993-10-27 | — | — | EP | disclosed |
| EP-0462986-B1 | IMIDAZOPYRIMIDINE ANTIALLERGY AGENTS | Pfizer Limited (GB) | 1993-10-06 | — | — | EP | disclosed |
| US-5250531-A | Antiallergens, antiinflammatory agents | PFIZER INC. (US) | 1993-10-05 | — | — | US | disclosed |
| EP-0530207-A1 | IMIDAZOPYRIDINE PAF ANTAGONISTS | Pfizer Limited (GB) | 1993-03-10 | — | — | EP | disclosed |
| EP-0466711-A1 | DIHYDROPYRIMIDINE ANTIALLERGY AGENTS. | PFIZER LTD (GB) | 1992-01-22 | — | — | EP | disclosed |
| EP-0462986-A1 | IMIDAZOPYRIMIDINE ANTIALLERGY AGENTS. | PFIZER LTD (GB) | 1992-01-02 | — | — | EP | disclosed |
| WO-1991017162-A1 | IMIDAZOPYRIDINE PAF ANTAGONISTS | PFIZER LIMITED (GB) | 1991-11-14 | — | — | WO | disclosed |
| WO-1990011281-A1 | DIHYDROPYRIMIDINE ANTIALLERGY AGENTS | PFIZER LIMITED (GB) | 1990-10-04 | — | — | WO | disclosed |
| WO-1990010632-A1 | IMIDAZOPYRIMIDINE ANTIALLERGY AGENTS | PFIZER LIMITED (GB) | 1990-09-20 | — | — | WO | disclosed |