Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524574 | 0.82 | MAPT (0.47) | TP53HSD17B10MEN1KMT2A | |
| SCHEMBL9868470 | 0.81 | TP53 (0.40) | TP53 | |
| SCHEMBL9727194 | 0.79 | TP53 (0.46) | TP53HSD17B10MEN1KMT2A | |
| SCHEMBL9870060 | 0.78 | MEN1 (0.48) | TP53MEN1KMT2A | |
| SCHEMBL9524668 | 0.76 | HSD17B10 (0.55) | HSD17B10MEN1KMT2A | |
| SCHEMBL9525676 | 0.76 | HSD17B10 (0.48) | HSD17B10MEN1KMT2A | |
| SCHEMBL9524646 | 0.76 | TP53 (0.45) | TP53MEN1KMT2A | |
| SCHEMBL9525496 | 0.75 | MAPT (0.53) | HSD17B10MEN1KMT2A | |
| SCHEMBL9525015 | 0.75 | TP53 (0.40) | TP53HSD17B10MEN1KMT2A | |
| SCHEMBL7505146 | 0.75 | HSD17B10 (0.59) | HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530207-A1 | IMIDAZOPYRIDINE PAF ANTAGONISTS | Pfizer Limited (GB) | 1993-03-10 | — | — | EP | disclosed |
| WO-1991017162-A1 | IMIDAZOPYRIDINE PAF ANTAGONISTS | PFIZER LIMITED (GB) | 1991-11-14 | — | — | WO | disclosed |