Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 7/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | GAA | P10253 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | THRB | P10828 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11538185 | 0.83 | ALDH1A1 (0.56) | ALDH1A1MAPTRAB9AGAANPC1 | |
| SCHEMBL22140743 | 0.81 | MEN1 (0.67) | MAPTRAB9AGAAMAPK1NPC1 | |
| SCHEMBL11712938 | 0.80 | NR4A1 (0.59) | ALDH1A1MAPTRAB9AGAAKDM4E | |
| SCHEMBL22140747 | 0.80 | KMT2A (0.51) | ALDH1A1MAPTRAB9AGAAKDM4E | |
| SCHEMBL4584836 | 0.79 | MAPT (0.62) | ALDH1A1MAPTRAB9AGAAKDM4E | |
| SCHEMBL13809404 | 0.78 | ALDH1A1 (1.00) | ALDH1A1MAPTRAB9AGAAKDM4E | |
| SCHEMBL1029577 | 0.78 | HPGD (0.52) | ALDH1A1MAPTRAB9AGAATDP1 | |
| SCHEMBL11587408 | 0.78 | GAA (0.63) | ALDH1A1MAPTGAARECQLTDP1 | |
| SCHEMBL16174783 | 0.78 | MAPT (0.59) | ALDH1A1MAPTRAB9AGAAKDM4E | |
| SCHEMBL1459772 | 0.76 | MAPT (1.00) | ALDH1A1MAPTRAB9AGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020127165-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-06-25 | — | — | WO | disclosed |
| EP-0523046-A1 | 2-ANILINO PHENYLACETIC ACID DERIVATIVES AS INHIBITORS OF PLA 2? AND LIPOXYGENASE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-01-20 | — | — | EP | disclosed |
| US-5159085-A | Antiinflammatory, antiallergens, cytoprotective agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-10-27 | — | — | US | disclosed |
| US-5021576-A | Antiinflammatory, antiarthritic, hypotensive, anticarcinogenic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-06-04 | — | — | US | disclosed |
| WO-1991006539-A1 | 2-ANILINO PHENYLACETIC ACID DERIVATIVES AS INHIBITORS OF PLA2 AND LIPOXYGENASE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-05-16 | — | — | WO | disclosed |