Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | THRB | P10828 | 2/20 | 0.62 |
| ▸ | RECQL | P46063 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | MMP14 | P50281 | 1/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1921461 | 0.86 | RAB9A (0.72) | MAPTRAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL11770932 | 0.84 | POLB (0.50) | MAPTRAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL4002574 | 0.84 | MAPK14 (0.49) | MAPTRAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL14598925 | 0.83 | AKR1C3 (0.63) | MAPTKMT2AMAPK1MEN1ALOX12 | |
| SCHEMBL16174783 | 0.83 | MAPT (0.59) | MAPTRAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL27546857 | 0.82 | MAPT (0.73) | MAPTRAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL11123242 | 0.81 | KDM4E (0.54) | MAPTRAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL6352626 | 0.81 | L3MBTL1 (0.55) | MAPTGAAKMT2AMAPK1MEN1 | |
| SCHEMBL9524958 | 0.79 | ALDH1A1 (0.65) | MAPTRAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL17201829 | 0.79 | MAPT (0.71) | MAPTRAB9AGAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58120670-A | — | — | None | — | — | JP | disclosed |
| JP-58180557-A | — | — | None | — | — | JP | disclosed |
| EP-1903023-A1 | Method for manufacturing arylamines | Archimica GmbH (DE) | 2008-03-26 | — | — | EP | disclosed |
| US-20080039633-A1 | Process for preparing arylamines | ARCHIMICA GMBH (DE) | 2008-02-14 | — | — | US | disclosed |
| US-5166350-A | Process for the manufacture of fluoran compounds | CIBA-GEIGY CORPORATION (US) | 1992-11-24 | — | — | US | disclosed |
| EP-0324344-A1 | Fluoran derivatives | BASF Aktiengesellschaft (DE) | 1989-07-19 | — | — | EP | disclosed |
| EP-0155796-B1 | 6-TETRAHYDROFURFURYLAMINOFLUORAN COMPOUND USEFUL AS A COLOR FORMER | HODOGAYA CHEMICAL CO., LTD. (JP) | 1988-09-14 | — | — | EP | disclosed |
| US-4694088-A | Fluoran compounds | HODOGAYA CHEMICAL CO., LTD. (JP) | 1987-09-15 | — | — | US | disclosed |
| US-4642663-A | 6-tetrahydrofurfurylaminofluoran compound useful as a color former on an heat sensitive recording sheet | HODOGAYA CHEMICAL CO., LTD. (JP) | 1987-02-10 | — | — | US | disclosed |
| US-4597795-A | HEAT SENSITIVE RECORDING | HODOGAYA CHEMICAL CO., LTD. (JP) | 1986-07-01 | — | — | US | disclosed |
| EP-0180643-A1 | FLUORAN COMPOUNDS | HODOGAYA CHEMICAL CO., LTD. (JP) | 1986-05-14 | — | — | EP | disclosed |
| EP-0176161-A1 | Novel fluoran compounds and production and use thereof | TAOKA CHEMICAL CO., LTD (JP) | 1986-04-02 | — | — | EP | disclosed |
| EP-0155796-A2 | 6-Tetrahydrofurfurylaminofluoran compound useful as a color former | HODOGAYA CHEMICAL CO., LTD. (JP) | 1985-09-25 | — | — | EP | disclosed |
| EP-0048026-B1 | HEAT SENSITIVE RECORD SHEET | HODOGAYA CHEMICAL CO., LTD. (JP) | 1984-12-19 | — | — | EP | disclosed |
| JP-S58180557-A | FLUORAN DERIVATIVE | RICOH CO LTD | 1983-10-22 | — | — | JP | disclosed |
| US-RE31412-E | FLUORAN COMPOUND AS COLOR-FORMER | YAMAMOTO KAGAKU GOSEI KABUSHIKI KAISHA (JP) | 1983-10-11 | — | — | US | disclosed |
| JP-S58120670-A | NOVEL FLUORAN DERIVATIVE | RICOH CO LTD | 1983-07-18 | — | — | JP | disclosed |
| US-4364999-A | 2-(2-CHLOROPHENYL)AMINO-6-DI-PROPYL-OR BUTYL-AMINOFLUORAN | HODOGAYA CHEMICAL CO., LTD. (JP) | 1982-12-21 | — | — | US | disclosed |
| EP-0048026-A1 | Heat sensitive record sheet | HODOGAYA CHEMICAL CO., LTD. (JP) | 1982-03-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039633-A1 | Process for preparing arylamines | BRD4, AHR, BRD1 | MAPT 3565/4885RAB9A 1931/4885GAA 4732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.