Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.45 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ROS1 | P08922 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524646 | 0.85 | TP53 (0.45) | MEN1KMT2ATP53 | |
| SCHEMBL9524574 | 0.78 | MAPT (0.47) | MEN1KMT2ATP53 | |
| SCHEMBL9524966 | 0.78 | TP53 (0.46) | MEN1KMT2ATP53 | |
| SCHEMBL9727194 | 0.77 | TP53 (0.46) | MEN1KMT2ATP53ROCK2 | |
| SCHEMBL9868911 | 0.76 | DRD1 (0.40) | — | |
| SCHEMBL9332789 | 0.76 | KLKB1 (0.51) | MEN1KMT2ALMNA | |
| SCHEMBL9868470 | 0.74 | TP53 (0.40) | TP53 | |
| SCHEMBL7774816 | 0.74 | DRD1 (0.49) | MEN1KMT2A | |
| SCHEMBL9524861 | 0.73 | TP53 (0.39) | MEN1KMT2ATP53 | |
| SCHEMBL9525557 | 0.73 | MAPK1 (0.51) | MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991017162-A1 | IMIDAZOPYRIDINE PAF ANTAGONISTS | PFIZER LIMITED (GB) | 1991-11-14 | — | — | WO | disclosed |