SCHEMBL9524646

SCHEMBL9524646

Cc1nc2cnccc2n1-c1ccc(CNCc2ccccc2Cl)cc1

nearest known ligand 0.57

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.45
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9870060 0.85 MEN1 (0.48) TP53MEN1KMT2A
SCHEMBL9868911 0.80 DRD1 (0.40)
SCHEMBL9879809 0.79 TP53 (0.41) TP53MEN1KMT2A
SCHEMBL9525557 0.77 MAPK1 (0.51) MEN1KMT2A
SCHEMBL9524574 0.76 MAPT (0.47) TP53MEN1KMT2APOLB
SCHEMBL9524966 0.76 TP53 (0.46) TP53MEN1KMT2A
SCHEMBL9869257 0.75 RPS6KA5 (0.43) MEN1KMT2A
SCHEMBL7774816 0.75 DRD1 (0.49) MEN1KMT2A
SCHEMBL16168685 0.75 MEN1 (0.53) MEN1KMT2A
SCHEMBL9727194 0.75 TP53 (0.46) TP53MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0530207-A1 IMIDAZOPYRIDINE PAF ANTAGONISTS Pfizer Limited (GB) 1993-03-10 EP disclosed
WO-1991017162-A1 IMIDAZOPYRIDINE PAF ANTAGONISTS PFIZER LIMITED (GB) 1991-11-14 WO disclosed