Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9525689 | 0.81 | KMT2A (0.51) | KMT2AALDH1A1OPRM1OPRD1SMN1; SMN2 | |
| SCHEMBL9524476 | 0.80 | HTT (0.45) | KMT2AALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9524632 | 0.79 | HTT (0.47) | KMT2AALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9525452 | 0.78 | HTT (0.56) | KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9524303 | 0.77 | HTT (0.50) | KMT2AALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9525869 | 0.76 | HTT (0.44) | KMT2AALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9525530 | 0.76 | HTT (0.46) | KMT2AALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9526168 | 0.76 | HTT (0.46) | KMT2AALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9525423 | 0.76 | EGFR (0.47) | KMT2AALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9524339 | 0.76 | EGFR (0.47) | KMT2AALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301751-B1 | PYRIDINIUM DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-4962113-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1990-10-09 | — | — | US | disclosed |
| EP-0301751-A1 | Pyridinium derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-02-01 | — | — | EP | disclosed |