Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9525217 | 0.81 | KMT2A (0.47) | KMT2AOPRM1OPRD1SMN1; SMN2NPC1 | |
| SCHEMBL9524632 | 0.78 | HTT (0.47) | KMT2AMEN1POLBHCAR2KDM4E | |
| SCHEMBL9525452 | 0.78 | HTT (0.56) | KMT2APOLBHCAR2KDM4EMAPT | |
| SCHEMBL9524339 | 0.75 | EGFR (0.47) | KMT2AMEN1CYP3A4POLBHCAR2 | |
| SCHEMBL9525423 | 0.75 | EGFR (0.47) | KMT2AMEN1CYP3A4POLBHCAR2 | |
| SCHEMBL9528745 | 0.75 | HTT (0.44) | KMT2AMEN1POLBHCAR2KDM4E | |
| SCHEMBL24167448 | 0.75 | KDM4E (0.42) | KMT2AMEN1CYP3A4POLBKDM4E | |
| SCHEMBL9525657 | 0.74 | KMT2A (0.58) | KMT2ACYP1A2CYP3A4CYP2C19POLB | |
| SCHEMBL10874128 | 0.72 | POLB (0.49) | KMT2ACYP1A2CYP3A4CYP2C19POLB | |
| SCHEMBL9524476 | 0.72 | HTT (0.45) | KMT2AMEN1POLBHCAR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301751-B1 | PYRIDINIUM DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-4962113-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1990-10-09 | — | — | US | disclosed |
| EP-0301751-A1 | Pyridinium derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-02-01 | — | — | EP | disclosed |