Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | G6PD | P11413 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.41 |
| ▸ | TUBB | P07437 | 2/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5300778 | 0.83 | MAPT (0.58) | MAPTMEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL25896876 | 0.80 | MAPT (0.54) | MAPTMEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL2674642 | 0.78 | MEN1 (0.53) | MAPTMEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL9348606 | 0.78 | MAPT (0.56) | MAPTMEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL12932855 | 0.77 | MAPK1 (0.51) | MAPTMEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL12963097 | 0.77 | G6PD (0.59) | MAPTMEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL11197844 | 0.75 | MEN1 (0.50) | MAPTMEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL27518757 | 0.75 | MAPT (0.46) | MAPTMEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL11062887 | 0.75 | MEN1 (0.50) | MAPTMEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL4099563 | 0.74 | MAPT (0.49) | MAPTMEN1KMT2ASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301751-B1 | PYRIDINIUM DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-4962113-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1990-10-09 | — | — | US | disclosed |
| EP-0301751-A1 | Pyridinium derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-02-01 | — | — | EP | disclosed |