Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25896876 | 0.82 | MAPT (0.54) | MAPTMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL5300778 | 0.81 | MAPT (0.58) | MAPTMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL9525229 | 0.78 | MAPT (0.54) | MAPTMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL12932855 | 0.75 | MAPK1 (0.51) | MAPTMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL12963097 | 0.75 | G6PD (0.59) | MAPTMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL2097204 | 0.73 | ACHE (0.54) | MAPTMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL2674642 | 0.72 | MEN1 (0.53) | MAPTMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL4099563 | 0.72 | MAPT (0.49) | MAPTMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL29254055 | 0.72 | MEN1 (1.00) | MAPTMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL1651683 | 0.71 | ACHE (0.52) | MAPTMEN1KMT2AMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296602-A | Condensing substituted ortho-halo- or ortho-aminobenzoic acid with meta-halo- or meta-aminoanisole, cyclizing, N-alkylating, de-O-methylating | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1994-03-22 | — | — | US | disclosed |
| WO-1992016509-A1 | MULTISUBSTITUTED 1-HYDROXY-9-ACRIDONES WITH ANTICANCER ACTIVITY | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-10-01 | — | — | WO | disclosed |