Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526042 | 1.00 | TRPV1 (0.47) | TRPV1MEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL9524189 | 0.95 | MEN1 (0.49) | TRPV1MEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL9524021 | 0.88 | MEN1 (0.44) | TRPV1MEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL9524407 | 0.88 | MAPK1 (0.45) | TRPV1MEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL9525343 | 0.87 | ALDH1A1 (0.44) | TRPV1MEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL9525576 | 0.87 | TSHR (0.45) | TRPV1MEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL9525216 | 0.86 | MAPT (0.43) | TRPV1MEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL9526051 | 0.85 | MEN1 (0.44) | TRPV1MEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL10401724 | 0.82 | TRPV1 (0.52) | TRPV1SMN1; SMN2POLBHTTMAPK1 | |
| Hydrochloric Acid SCHEMBL9528303 | 0.82 | ALDH1A1 (0.42) | TRPV1MEN1KMT2ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301751-B1 | PYRIDINIUM DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-03-10 | — | — | EP | disclosed |