Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PRCP | P42785 | 2/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526410 | 0.93 | TSHR (0.58) | TSHRNPSR1SLC6A2SLC6A4SLC18A2 | |
| SCHEMBL9525139 | 0.88 | TSHR (0.52) | TSHRNPSR1SLC6A2SLC6A4SLC18A2 | |
| SCHEMBL700153 | 0.87 | TSHR (0.55) | TSHRNPSR1SLC6A2SLC6A4SLC18A2 | |
| SCHEMBL9852994 | 0.86 | TSHR (0.57) | TSHRNPSR1SLC6A2SLC6A4SLC18A2 | |
| SCHEMBL9853004 | 0.83 | TSHR (0.59) | TSHRNPSR1SLC6A2SLC6A4SLC18A2 | |
| SCHEMBL23119015 | 0.81 | TSHR (0.60) | TSHRNPSR1SLC6A2SLC6A4SLC18A2 | |
| SCHEMBL4853532 | 0.81 | TSHR (0.60) | TSHRNPSR1SLC6A2SLC6A4SLC18A2 | |
| SCHEMBL9525152 | 0.81 | TSHR (0.50) | TSHRNPSR1SLC6A2SLC6A4SLC18A2 | |
| Hydrochloric Acid SCHEMBL19953531 | 0.80 | TSHR (0.62) | TSHRNPSR1SLC6A2SLC6A4SLC18A2 | |
| Hydrochloric Acid SCHEMBL2790413 | 0.80 | TSHR (0.62) | TSHRNPSR1SLC6A2SLC6A4SLC18A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301751-B1 | PYRIDINIUM DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-4962113-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1990-10-09 | — | — | US | disclosed |
| EP-0301751-A1 | Pyridinium derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-02-01 | — | — | EP | disclosed |