Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PRCP | P42785 | 2/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853004 | 0.92 | TSHR (0.59) | TSHRNPSR1SLC6A2SLC6A4HTR2C | |
| SCHEMBL9525353 | 0.86 | TSHR (0.55) | TSHRNPSR1SLC6A2SLC6A4OPRM1 | |
| SCHEMBL700153 | 0.86 | TSHR (0.55) | TSHRNPSR1SLC6A2SLC6A4OPRM1 | |
| SCHEMBL9526410 | 0.84 | TSHR (0.58) | TSHRNPSR1SLC6A2SLC6A4OPRM1 | |
| SCHEMBL23119015 | 0.80 | TSHR (0.60) | TSHRNPSR1SLC6A2SLC6A4OPRM1 | |
| SCHEMBL4853532 | 0.80 | TSHR (0.60) | TSHRNPSR1SLC6A2SLC6A4OPRM1 | |
| Hydrochloric Acid SCHEMBL2790413 | 0.79 | TSHR (0.62) | TSHRNPSR1SLC6A2SLC6A4OPRM1 | |
| Hydrochloric Acid SCHEMBL19953531 | 0.79 | TSHR (0.62) | TSHRNPSR1SLC6A2SLC6A4OPRM1 | |
| SCHEMBL9525139 | 0.79 | TSHR (0.52) | TSHRNPSR1SLC6A2SLC6A4OPRM1 | |
| SCHEMBL9525152 | 0.77 | TSHR (0.50) | TSHRNPSR1SLC6A2SLC6A4OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441226-A1 | (cyanomethyl)pyridines useful as PAF antagonists | J. URIACH & CIA. S.A. (ES) | 1991-08-14 | — | — | EP | disclosed |