Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | BRD2 | P25440 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.41 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701615 | 0.88 | KMT2A (0.59) | CA5AKMT2ACREBBPMEN1BRD4 | |
| SCHEMBL7595095 | 0.85 | CA12 (0.54) | KMT2ACREBBPMEN1BRD4BRD2 | |
| SCHEMBL7994043 | 0.84 | HPGD (0.50) | CA5AKMT2ACREBBPMEN1BRD4 | |
| SCHEMBL713400 | 0.82 | CA12 (0.63) | KMT2ACREBBPMEN1BRD4BRD2 | |
| SCHEMBL28494202 | 0.82 | CA5A (0.53) | CA5ACA12CA1CA2CA7 | |
| SCHEMBL7991107 | 0.82 | CA5A (0.53) | CA5ASMN1; SMN2TSHRMAOBMAPT | |
| SCHEMBL5415007 | 0.82 | CA12 (0.73) | KMT2ACREBBPMEN1BRD4BRD2 | |
| SCHEMBL20239499 | 0.81 | KMT2A (0.54) | KMT2ACREBBPMEN1BRD4BRD2 | |
| SCHEMBL1190221 | 0.81 | CREBBP (0.47) | KMT2ACREBBPMEN1BRD4BRD2 | |
| SCHEMBL13703965 | 0.81 | CA5A (0.52) | CA5AALDH1A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550576-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |