Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA7 | P43166 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.54 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.53 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.51 |
| ▸ | HCAR1 | Q9BXC0 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | BRD2 | P25440 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2655120 | 0.88 | PLA2G2A (0.65) | PLA2G2AKMT2AMEN1TP53PKM | |
| SCHEMBL3184334 | 0.88 | PLA2G2A (0.59) | PLA2G2AKMT2AMEN1TP53PKM | |
| SCHEMBL9525522 | 0.85 | CA5A (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL713400 | 0.82 | CA12 (0.63) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5415007 | 0.82 | CA12 (0.73) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31442766 | 0.82 | PLA2G2A (0.82) | PLA2G2AKMT2ATP53PLA2G4BTSHR | |
| SCHEMBL18311268 | 0.81 | PLA2G2A (0.57) | CA1CA2PLA2G2AKMT2AMEN1 | |
| SCHEMBL29784186 | 0.81 | PLA2G2A (0.53) | PLA2G2AKMT2AMEN1TP53PKM | |
| SCHEMBL2279445 | 0.81 | PLA2G2A (0.53) | PLA2G2AKMT2AMEN1TP53PKM | |
| SCHEMBL12861036 | 0.81 | TPMT (0.57) | PLA2G2AHCAR1KMT2AMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667470-B | Lubricating base oil | 花王株式会社 | 2023-10-20 | — | — | CN | disclosed |
| EP-1000038-B1 | NOVEL PYRIMIDIN DERIVATIVES | ASTRAZENECA AB (SE) | 2002-11-06 | — | — | EP | disclosed |
| EP-1000038-A1 | NOVEL PYRIMIDIN DERIVATIVES | AstraZeneca UK Limited (GB) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999005123-A1 | NOVEL PYRIMIDIN DERIVATIVES | ASTRAZENECA UK LIMITED (GB) | 1999-02-04 | — | — | WO | disclosed |