Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | NPY5R | Q15761 | 15/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9594529 | 0.84 | POLB (0.67) | POLBNPY5RKMT2A | |
| SCHEMBL9592489 | 0.84 | POLB (0.67) | POLBNPY5RKMT2AMEN1MAPT | |
| SCHEMBL9184563 | 0.83 | POLB (1.00) | POLBNPY5RKMT2AMAPK1 | |
| SCHEMBL9879206 | 0.82 | POLB (0.80) | POLBNPY5RKMT2AMAPK1 | |
| SCHEMBL9870858 | 0.82 | POLB (0.65) | POLBNPY5RKMT2A | |
| SCHEMBL9593791 | 0.82 | POLB (0.65) | POLBNPY5RKMT2A | |
| SCHEMBL9869664 | 0.82 | POLB (0.65) | POLBNPY5RKMT2AMEN1MAPT | |
| SCHEMBL21904916 | 0.81 | POLB (0.71) | POLBNPY5RKMT2A | |
| SCHEMBL9592706 | 0.81 | POLB (0.67) | POLBNPY5RKMT2A | |
| SCHEMBL13523080 | 0.80 | POLB (0.61) | POLBNPY5RKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5286945-A | — | — | None | — | — | JP | disclosed |
| JP-H05286945-A | DERIVATIVE OF 1-PHENYL-1,4-DIHYDRO-3-HYDROXY-4-OXOPYRIDAZINE, ITS PREPARATION AND ITS APPLICATION FOR THERAPY | PIERRE FABRE MEDICAMENT | 1993-11-02 | — | — | JP | disclosed |
| US-5254554-A | Anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1993-10-19 | — | — | US | disclosed |