Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | NPY5R | Q15761 | 11/20 | 0.54 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9184563 | 0.89 | POLB (1.00) | POLBKMT2ANPY5RMAPK1RIPK1 | |
| SCHEMBL9592489 | 0.82 | POLB (0.67) | POLBKMT2ANPY5RSCN9ACYP2C9 | |
| SCHEMBL9525617 | 0.82 | POLB (0.71) | POLBKMT2ANPY5RMAPK1 | |
| SCHEMBL29827072 | 0.82 | MAPK1 (0.78) | KMT2AMAPK1RIPK1 | |
| SCHEMBL9594529 | 0.80 | POLB (0.67) | POLBKMT2ANPY5R | |
| SCHEMBL21904916 | 0.80 | POLB (0.71) | POLBKMT2ANPY5RRIPK1 | |
| SCHEMBL9592706 | 0.80 | POLB (0.67) | POLBKMT2ANPY5R | |
| SCHEMBL519033 | 0.79 | ALDH1A1 (0.60) | POLBKMT2ACYP2C9CYP3A4 | |
| SCHEMBL9870858 | 0.78 | POLB (0.65) | POLBKMT2ANPY5R | |
| SCHEMBL9593791 | 0.78 | POLB (0.65) | POLBKMT2ANPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5059599-A | Anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1991-10-22 | — | — | US | disclosed |