Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | NPY5R | Q15761 | 12/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9525617 | 0.82 | POLB (0.71) | POLBNPY5RKMT2AMEN1MAPT | |
| SCHEMBL9592489 | 0.82 | POLB (0.67) | POLBNPY5RKMT2ACTSKCYP1A2 | |
| SCHEMBL9594529 | 0.82 | POLB (0.67) | POLBNPY5RKMT2A | |
| SCHEMBL9593791 | 0.80 | POLB (0.65) | POLBNPY5RKMT2ACTSKCYP1A2 | |
| SCHEMBL9870858 | 0.80 | POLB (0.65) | POLBNPY5RKMT2ACTSK | |
| SCHEMBL9184563 | 0.79 | POLB (1.00) | POLBNPY5RKMT2A | |
| SCHEMBL13523080 | 0.78 | POLB (0.61) | POLBNPY5RKMT2AGAAMAPT | |
| SCHEMBL29576667 | 0.78 | POLB (0.61) | POLBNPY5RKMT2AGAAMAPT | |
| SCHEMBL9879206 | 0.78 | POLB (0.80) | POLBNPY5RKMT2A | |
| SCHEMBL12167439 | 0.77 | POLB (0.57) | POLBNPY5RKMT2AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5059599-A | Anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1991-10-22 | — | — | US | disclosed |