Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | VCP | P55072 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KRAS | P01116 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9525625 | 1.00 | PTGS2 (0.64) | PTGS2CYP19A1KDM4EKMT2AALDH1A1 | |
| SCHEMBL9523759 | 0.92 | PTGS2 (0.69) | PTGS2CYP19A1KDM4EKMT2AALDH1A1 | |
| SCHEMBL9523755 | 0.92 | PTGS2 (0.69) | PTGS2CYP19A1KDM4EKMT2AALDH1A1 | |
| SCHEMBL9589680 | 0.87 | MAOB (0.64) | PTGS2KMT2AALDH1A1SMN1; SMN2TLR9 | |
| SCHEMBL9589678 | 0.87 | MAOB (0.64) | PTGS2KMT2AALDH1A1SMN1; SMN2TLR9 | |
| SCHEMBL10399340 | 0.84 | MAPT (0.58) | PTGS2KDM4EKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL1597196 | 0.82 | MAPT (0.66) | PTGS2CYP19A1KDM4EKMT2AALDH1A1 | |
| SCHEMBL9522627 | 0.82 | CYP19A1 (0.55) | PTGS2CYP19A1KDM4EKMT2AALDH1A1 | |
| SCHEMBL30839393 | 0.82 | MAPT (0.66) | PTGS2CYP19A1KDM4EKMT2AALDH1A1 | |
| SCHEMBL9522624 | 0.82 | CYP19A1 (0.55) | PTGS2CYP19A1KDM4EKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354583-B1 | DC-88A derivatives | KYOWA HAKKO KOGYO KK (JP) | 1993-11-03 | — | — | EP | disclosed |
| US-5117006-A | DC-88A DERIVATIVES USEFUL AS ANTITUMOR AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-05-26 | — | — | US | disclosed |
| US-5084468-A | Antitumor agents | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-01-28 | — | — | US | disclosed |
| EP-0354583-A1 | DC-88A derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-02-14 | — | — | EP | disclosed |