Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | FBP1 | P09467 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | COMT | P21964 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.49 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.49 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9522585 | 0.92 | MAPT (0.65) | MAPTALDH1A1LMNAKMT2ANPC1 | |
| SCHEMBL9522581 | 0.92 | MAPT (0.65) | MAPTALDH1A1LMNAKMT2ANPC1 | |
| SCHEMBL9589680 | 0.87 | MAOB (0.64) | MAPTALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL9589678 | 0.87 | MAOB (0.64) | MAPTALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL10670204 | 0.85 | MAOB (0.51) | MAPTALDH1A1LMNAKMT2ANPC1 | |
| SCHEMBL10398009 | 0.85 | FBP1 (0.47) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL9523652 | 0.84 | CYP1B1 (0.56) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL9523646 | 0.84 | CYP1B1 (0.56) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL9525619 | 0.84 | PTGS2 (0.64) | MAPTALDH1A1LMNAKMT2ANPC1 | |
| SCHEMBL9525625 | 0.84 | PTGS2 (0.64) | MAPTALDH1A1LMNAKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4975438-A | ANTICOAGULANT | HOFFMANN-LA ROCHE INC. (US) | 1990-12-04 | — | — | US | disclosed |
| US-4788206-A | CARDIOVASCULAR DISORDERS, PLATELETS | HOFFMANN-LA ROCHE INC. (US) | 1988-11-29 | — | — | US | disclosed |