Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9525350 | 0.95 | AGTR2 (0.50) | AGTR2AGTR1 | |
| SCHEMBL9526433 | 0.88 | AGTR1 (0.43) | AGTR2AGTR1 | |
| SCHEMBL9526081 | 0.84 | AGTR2 (0.53) | AGTR2AGTR1 | |
| SCHEMBL9527063 | 0.84 | AGTR2 (0.48) | AGTR2AGTR1 | |
| SCHEMBL9527008 | 0.80 | AGTR2 (0.50) | AGTR2AGTR1 | |
| SCHEMBL9530400 | 0.79 | AGTR2 (0.57) | AGTR2AGTR1 | |
| SCHEMBL9528173 | 0.79 | AGTR1 (0.51) | AGTR2AGTR1 | |
| SCHEMBL9526703 | 0.79 | AGTR1 (0.60) | AGTR1 | |
| SCHEMBL9526460 | 0.77 | AGTR2 (0.42) | AGTR2AGTR1 | |
| SCHEMBL9527046 | 0.76 | AGTR1 (0.39) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0523141-A4 | SUBSTITUTED PYRAZOLES, ISOXAZOLES AND ISOTHIAZOLES | — | 1993-04-21 | — | — | EP | claimed |
| EP-0523141-A1 | SUBSTITUTED PYRAZOLES, ISOXAZOLES AND ISOTHIAZOLES | MERCK & CO. INC. (US) | 1993-01-20 | — | — | EP | claimed |
| WO-1991015479-A1 | SUBSTITUTED PYRAZOLES, ISOXAZOLES AND ISOTHIAZOLES | MERCK & CO., INC. (US) | 1991-10-17 | — | — | WO | claimed |
| WO-1991015479-A1 | SUBSTITUTED PYRAZOLES, ISOXAZOLES AND ISOTHIAZOLES | MERCK & CO., INC. (US) | 1991-10-17 | — | — | WO | disclosed |