Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | GALK1 | P51570 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9525638 | 1.00 | MAPT (0.54) | MAPTKMT2AALDH1A1MEN1TDP1 | |
| SCHEMBL9567334 | 0.86 | KMT2A (0.50) | MAPTKMT2AALDH1A1MEN1TDP1 | |
| SCHEMBL9567336 | 0.86 | KMT2A (0.50) | MAPTKMT2AALDH1A1MEN1TDP1 | |
| SCHEMBL9524853 | 0.81 | MAPT (0.50) | MAPTKMT2AALDH1A1MEN1TDP1 | |
| SCHEMBL9524844 | 0.81 | MAPT (0.50) | MAPTKMT2AALDH1A1MEN1TDP1 | |
| SCHEMBL9525436 | 0.80 | MAPT (0.58) | MAPTKMT2AALDH1A1MEN1TDP1 | |
| SCHEMBL9525442 | 0.80 | MAPT (0.58) | MAPTKMT2AALDH1A1MEN1TDP1 | |
| SCHEMBL9524422 | 0.79 | KMT2A (0.75) | MAPTKMT2AALDH1A1MEN1TDP1 | |
| SCHEMBL9727216 | 0.79 | KMT2A (0.75) | MAPTKMT2AALDH1A1MEN1TDP1 | |
| SCHEMBL28967915 | 0.79 | MEN1 (0.71) | MAPTKMT2AALDH1A1MEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274642-B1 | HERBICIDAL AND FUNGICIDAL AGENTS BASED ON SUBSTITUTED PYRAZOLIN-5-ONE DERIVATIVES | BAYER AG (DE) | 1993-08-11 | — | — | EP | claimed |
| EP-0274642-B1 | HERBICIDAL AND FUNGICIDAL AGENTS BASED ON SUBSTITUTED PYRAZOLIN-5-ONE DERIVATIVES | BAYER AG (DE) | 1993-08-11 | — | — | EP | disclosed |