Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 11/20 | 0.50 |
| ▸ | MEN1 | O00255 | 10/20 | 0.50 |
| ▸ | MAPT | P10636 | 9/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | GALK1 | P51570 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9567336 | 1.00 | KMT2A (0.50) | KMT2AMEN1MAPTALDH1A1GAA | |
| SCHEMBL9525638 | 0.86 | MAPT (0.54) | KMT2AMEN1MAPTALDH1A1GAA | |
| SCHEMBL9525634 | 0.86 | MAPT (0.54) | KMT2AMEN1MAPTALDH1A1GAA | |
| SCHEMBL9567320 | 0.78 | GRM4 (0.38) | KMT2AMEN1MAPTALDH1A1GAA | |
| SCHEMBL6727781 | 0.75 | MAPT (0.47) | KMT2AMEN1MAPTALDH1A1GAA | |
| SCHEMBL6735314 | 0.74 | ALKBH3 (0.47) | MAPTGAAKDM4EPOLBCYP1A2 | |
| SCHEMBL6731277 | 0.72 | AMY1A (0.47) | MAPTALDH1A1CYP3A4CYP2C9RAB9A | |
| SCHEMBL9524411 | 0.71 | KMT2A (0.66) | KMT2AMEN1MAPTALDH1A1GAA | |
| SCHEMBL10422268 | 0.71 | KMT2A (0.66) | KMT2AMEN1MAPTALDH1A1GAA | |
| SCHEMBL28476777 | 0.71 | KMT2A (0.73) | KMT2AMEN1MAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532996-A1 | Diarylpyrazolinones | BAYER AG (DE) | 1993-03-24 | — | — | EP | disclosed |