Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 8/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 7/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 7/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2122482 | 0.76 | CCNA2 (0.32) | CDK2CCNA2CCNA1 | |
| SCHEMBL10535479 | 0.75 | MAPT (0.40) | CDK2AURKA | |
| SCHEMBL427782 | 0.71 | AHR (0.36) | CDK2CCNA2CCNA1 | |
| SCHEMBL1133642 | 0.71 | CCNA2 (0.34) | CDK2CCNA2CCNA1 | |
| SCHEMBL29941234 | 0.70 | MAPK10 (0.45) | MAPK10CDK2CCNA2CCNA1 | |
| SCHEMBL167198 | 0.68 | CCNA2 (0.31) | CDK2CCNA2CCNA1 | |
| SCHEMBL18222106 | 0.67 | NPC1 (0.38) | CDK2CCNA2CCNA1CDK1 | |
| SCHEMBL17491129 | 0.66 | CCNB2 (0.42) | CDK2CCNA2CCNA1CDK1 | |
| SCHEMBL12276833 | 0.66 | CCNA2 (0.33) | CDK2CCNA2CCNA1 | |
| SCHEMBL1395066 | 0.66 | TGFBR1 (0.36) | CDK2CCNA2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642784-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS AS INHIBITORS OF NLRP3 | PTC Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024145623-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS AS INHIBITORS OF NLRP3 | PTC THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |
| EP-0277791-B1 | CINNOLINE-CARBOXAMIDES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-06-02 | — | — | EP | disclosed |
| US-4826837-A | IMMUNOMODULATORS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1989-05-02 | — | — | US | disclosed |
| EP-0277791-A2 | Cinnoline-carboxamides and process for their preparation | FARMITALIA CARLO ERBA S.r.l. (IT) | 1988-08-10 | — | — | EP | disclosed |