Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 10/20 | 0.34 |
| ▸ | CDK2 | P24941 | 10/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 10/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Urea SCHEMBL1549376 | 0.91 | CCNA2 (0.43) | CCNA2CDK2CCNA1 | |
| SCHEMBL28420618 | 0.81 | AHR (0.31) | AHR | |
| SCHEMBL8565229 | 0.80 | AHR (0.37) | AHR | |
| SCHEMBL167198 | 0.75 | CCNA2 (0.31) | CCNA2CDK2CCNA1 | |
| SCHEMBL146383 | 0.73 | CYP3A4 (0.44) | AHR | |
| SCHEMBL9837616 | 0.73 | TGFBR1 (0.36) | CCNA2CDK2CCNA1TGFBR1 | |
| SCHEMBL2150779 | 0.73 | TNF (0.35) | AHR | |
| SCHEMBL1395066 | 0.73 | TGFBR1 (0.36) | CCNA2CDK2CCNA1TGFBR1 | |
| SCHEMBL9525697 | 0.71 | MAPK10 (0.34) | CCNA2CDK2CCNA1 | |
| SCHEMBL1133642 | 0.71 | CCNA2 (0.34) | CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1411 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114394967-B | Method for synthesizing pyrazoloquinoline derivative from 2-pyrazolyl aniline and 1, 3-dicarbonyl compound | 宁夏农林科学院农业资源与环境研究所（宁夏土壤与植物营养重点实验室） | 2023-12-15 | — | — | CN | claimed |
| CN-114213412-B | Method for synthesizing pyrazoloquinoline compound from 2-pyrazoloaniline derivative and ether under acid catalysis | 宁夏农林科学院农业资源与环境研究所（宁夏土壤与植物营养重点实验室） | 2022-12-30 | — | — | CN | claimed |
| CN-115252618-A | Application of pyrazoloquinoline derivative and pharmaceutical composition thereof | 大连医科大学附属第二医院 | 2022-11-01 | — | — | CN | claimed |
| CN-113896725-B | Pyrazoloquinoline compound and preparation method and application thereof | 沈阳药科大学 | 2022-10-25 | — | — | CN | claimed |
| CN-115073544-A | PARP inhibitor pyrazoloquinine derivative and synthesis method thereof | 上海应用技术大学 | 2022-09-20 | — | — | CN | claimed |
| CN-114394967-A | Method for synthesizing pyrazoloquinoline derivative from 2-pyrazoloaniline and 1, 3-dicarbonyl compound | 宁夏农林科学院农业资源与环境研究所（宁夏土壤与植物营养重点实验室） | 2022-04-26 | — | — | CN | claimed |
| CN-114213412-A | Method for synthesizing pyrazoloquinoline compound from 2-pyrazoloaniline derivative and ether under acid catalysis | 宁夏农林科学院农业资源与环境研究所（宁夏土壤与植物营养重点实验室） | 2022-03-22 | — | — | CN | claimed |
| CN-113896725-A | Pyrazoloquinoline compound and preparation method and application thereof | 沈阳药科大学 | 2022-01-07 | — | — | CN | claimed |
| US-11005082-B2 | Organic EL light-emitting element and manufacturing method thereof | SAKAI DISPLAY PRODUCTS CORPORATION (JP) | 2021-05-11 | — | — | US | claimed |
| US-10937985-B2 | Organic EL light-emitting element and manufacturing method thereof | SAKAI DISPLAY PRODUCTS CORPORATION (JP) | 2021-03-02 | — | — | US | claimed |
| EP-1413286-A1 | Dyeing composition comprising at least one heterocyclic oxidation base and at least one substituted 2,3-diaminopyridine as a coupling agent | L'OREAL (FR) | 2004-04-28 | — | — | EP | claimed |
| US-20030187014-A1 | Condensed pyrazole derivatives, process for producing the same and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-10-02 | — | — | US | claimed |
| EP-1270572-A1 | CONDENSED PYRAZOLE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-01-02 | — | — | EP | claimed |
| EP-1002535-A1 | New use of glutamate antagonists for the treatment of cancer | Ikonomidou, Hrissanthi (DE) | 2000-05-24 | — | — | EP | claimed |
| EP-0992240-A1 | THERAPEUTIC AGENT FOR ERECTION FAILURE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-12 | — | — | EP | claimed |
| WO-1998049219-A1 | PYRAZOL-BASED ELECTROLUMINESCENT POLYMERS AND THEIR USE IN ELECTROLUMINESCENT DEVICES | THE UNIVERSITY COURT OF NAPIER UNIVERSITY (GB) | 1998-11-05 | — | — | WO | claimed |
| EP-0476544-B1 | Pyrazoloquinoline derivatives | KYOWA HAKKO KOGYO KK (JP) | 1995-05-10 | — | — | EP | claimed |
| EP-0476544-A1 | Pyrazoloquinoline derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-03-25 | — | — | EP | claimed |
| US-4980379-A | ENHANCING EFFICIENCY BY REDUCING ADENOSINE LEVELS | THE UNIVERSITY OF VIRGINIA (US) | 1990-12-25 | — | — | US | claimed |
| US-4904472-A | Use of adenosine antagonists in the treatment of bradyarrhythmias and mechanical dysfunction associated with cardiopulmonary resuscitation | THE UNIVERSITY OF VIRGINIA ALUMNI PATENT FOUNDATION (US) | 1990-02-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187014-A1 | Condensed pyrazole derivatives, process for producing the same and use thereof | PTGS1, PTGIS, IL5 | AHR 218/4885CCNA2 2520/4885CDK2 193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.