Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7505146 | 0.83 | HSD17B10 (0.59) | SMN1; SMN2MEN1KMT2AHSD17B10DRD1 | |
| SCHEMBL9384977 | 0.80 | HSD17B10 (0.49) | SMN1; SMN2MEN1KMT2AHSD17B10DRD1 | |
| SCHEMBL9559464 | 0.80 | HSD17B10 (0.47) | SMN1; SMN2MEN1KMT2AHSD17B10DRD1 | |
| SCHEMBL9524668 | 0.80 | HSD17B10 (0.55) | SMN1; SMN2MEN1KMT2AHSD17B10HTT | |
| SCHEMBL9525676 | 0.79 | HSD17B10 (0.48) | SMN1; SMN2MEN1KMT2AHSD17B10DRD1 | |
| SCHEMBL9523968 | 0.79 | HSD17B10 (0.48) | SMN1; SMN2MEN1KMT2AHSD17B10DRD1 | |
| SCHEMBL9869004 | 0.79 | SMN1; SMN2 (0.52) | SMN1; SMN2DRD1 | |
| SCHEMBL9527192 | 0.78 | TBXAS1 (0.48) | SMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9697856 | 0.78 | MEN1 (0.45) | SMN1; SMN2MEN1KMT2AHSD17B10DRD1 | |
| Hydrochloric Acid SCHEMBL9523368 | 0.78 | MEN1 (0.45) | SMN1; SMN2MEN1KMT2AHSD17B10DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462986-B1 | IMIDAZOPYRIMIDINE ANTIALLERGY AGENTS | Pfizer Limited (GB) | 1993-10-06 | — | — | EP | disclosed |
| EP-0530207-A1 | IMIDAZOPYRIDINE PAF ANTAGONISTS | Pfizer Limited (GB) | 1993-03-10 | — | — | EP | disclosed |
| WO-1991017162-A1 | IMIDAZOPYRIDINE PAF ANTAGONISTS | PFIZER LIMITED (GB) | 1991-11-14 | — | — | WO | disclosed |