Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 3/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CLPP | Q16740 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9523403 | 0.94 | F3 (0.36) | FNTAPGGT1BFNTBCTSLCLPP | |
| SCHEMBL9525917 | 0.92 | CNR1 (0.42) | CTSLCNR1POLB | |
| SCHEMBL9525427 | 0.92 | KMT2A (0.33) | KMT2AMAPTCNR1 | |
| SCHEMBL9525756 | 0.88 | CARM1 (0.32) | KMT2AMAPTCNR1 | |
| SCHEMBL9523565 | 0.87 | TAS1R3 (0.36) | KMT2AMAPTMAPK1ATMCTSL | |
| SCHEMBL9522404 | 0.87 | KMT2A (0.41) | KMT2AMAPT | |
| SCHEMBL9522547 | 0.86 | CNR1 (0.39) | CTSLCNR1 | |
| SCHEMBL9523370 | 0.86 | KDR (0.34) | KMT2AMAPT | |
| SCHEMBL9316750 | 0.85 | PIK3CD (0.34) | — | |
| SCHEMBL9522525 | 0.84 | KEAP1 (0.35) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0420883-B1 | TRICYCLIC 3-OXO-PROPANENITRILE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | ERBA CARLO SPA (IT) | 1993-11-03 | — | — | EP | disclosed |
| US-5166152-A | Immunostimulants, bactericides, viricides, antitumor agents | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-11-24 | — | — | US | disclosed |
| EP-0420883-A1 | TRICYCLIC 3-OXO-PROPANENITRILE DERIVATIVES AND PROCESS FOR THEIR PREPARATION. | ERBA CARLO SPA (IT) | 1991-04-10 | — | — | EP | disclosed |
| WO-1989012638-A1 | TRICYCLIC 3-OXO-PROPANENITRILE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.R.L. (IT) | 1989-12-28 | — | — | WO | disclosed |