Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5805153 | 0.88 | SMN1; SMN2 (0.49) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL2798824 | 0.86 | SMN1; SMN2 (0.47) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL1624311 | 0.84 | SMN1; SMN2 (0.51) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL9363322 | 0.84 | TDP1 (0.49) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL9524232 | 0.82 | SMN1; SMN2 (0.41) | MEN1KMT2ALMNASMN1; SMN2CYP3A4 | |
| SCHEMBL8466175 | 0.82 | TP53 (0.51) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL5107520 | 0.81 | SMN1; SMN2 (0.47) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL25960252 | 0.81 | SMN1; SMN2 (0.47) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL5090319 | 0.80 | MEN1 (0.50) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL2800164 | 0.80 | SMN1; SMN2 (0.46) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301751-B1 | PYRIDINIUM DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-4962113-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1990-10-09 | — | — | US | disclosed |
| EP-0301751-A1 | Pyridinium derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-02-01 | — | — | EP | disclosed |