SCHEMBL1624311

SCHEMBL1624311

CC(C)(C)OC(=O)N(CCO)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
F2 P00734 3/20 0.47
TP53 P04637 2/20 0.46
ALDH1A1 P00352 3/20 0.43
TSHR P16473 2/20 0.43
GLA P06280 1/20 0.43
HDAC3 O15379 1/20 0.43
HDAC4 P56524 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC10 Q969S8 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
NCOR2 Q9Y618 1/20 0.43
L3MBTL1 Q9Y468 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5805153 0.91 SMN1; SMN2 (0.49) SMN1; SMN2MEN1KMT2ACYP3A4CYP2C9
SCHEMBL2798824 0.89 SMN1; SMN2 (0.47) SMN1; SMN2MEN1KMT2ACYP3A4CYP2C9
SCHEMBL27572033 0.87 TP53 (0.54) SMN1; SMN2MEN1KMT2ACYP3A4CYP2C9
SCHEMBL5090319 0.86 MEN1 (0.50) SMN1; SMN2MEN1KMT2ACYP3A4CYP2C9
SCHEMBL4312600 0.86 MEN1 (0.50) SMN1; SMN2MEN1KMT2ACYP3A4CYP2C9
SCHEMBL25736671 0.86 MEN1 (0.50) SMN1; SMN2MEN1KMT2ACYP3A4CYP2C9
SCHEMBL9407535 0.86 MEN1 (0.50) SMN1; SMN2MEN1KMT2ACYP3A4CYP2C9
SCHEMBL9525952 0.84 KDM4E (0.45) SMN1; SMN2MEN1KMT2ACYP3A4CYP2C9
SCHEMBL3657533 0.84 MT-CO2 (0.46) MEN1KMT2ACYP3A4F2SSTR4
SCHEMBL19317380 0.84 F2 (0.50) SMN1; SMN2MEN1KMT2ACYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117624061-A Production process of oxaagoli sodium 宣城美诺华药业有限公司 2024-03-01 CN claimed
CN-109956906-B Preparation method of key intermediate of oxalagogri 奥锐特药业股份有限公司 2021-01-29 CN claimed
CN-121298990-A Detection method of Boc-D-phenylglycinol isomer 金陵药业股份有限公司 2026-01-09 CN disclosed
US-20250092016-A1 COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CORONAVIRAL RELATED DISEASES NOVARTIS AG (CH) 2025-03-20 US disclosed
US-20250084042-A1 Elagolix Sodium Compositions and Processes ABBVIE INC. 2025-03-13 US disclosed
EP-4031533-B1 PROCESS FOR PREPARING ELAGOLIX SODIUM AND INTERMEDIATES THEREOF SCINOPHARM TAIWAN LTD (TW) 2025-01-01 EP disclosed
CN-118580178-A Method for synthesizing C-4 alkylpyridine by taking alcohol as alkylating reagent 陕西师范大学 2024-09-03 CN disclosed
CN-118459410-A Synthesis method of byproducts in oxaragroli intermediate synthesis route 诚达药业股份有限公司 2024-08-09 CN disclosed
EP-4373814-A1 COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CORONAVIRAL RELATED DISEASES Novartis AG (CH) 2024-05-29 EP disclosed
CN-117624061-A Production process of oxaagoli sodium 宣城美诺华药业有限公司 2024-03-01 CN disclosed
US-11840519-B2 Process for the synthesis of the sodium salt of 4-[[(1R)-2-[5-(2-fluoro-3-methoxyphenyl)-3-[[2-fluoro-6-(trifluoromethyl)-phenyl]methyl]-3,6-dihydro-4-methyl-2.6-dioxo-1(2H)-pyrimidinyl]-1-phenylethyl]amino]-butanoic acid (elagolix sodium salt) and intermediates of said process INDUSTRIALE CHIMICA S.R.L. (IT) 2023-12-12 US disclosed
WO-2000076970-A2 SERINE PROTEASE INHIBITORS ELI LILLY AND COMPANY (US) 2000-12-21 WO disclosed
EP-1012166-A1 1-AMINO-7-ISOQUINOLINE DERIVATIVES AS SERINE PROTEASE INHIBITORS Protherics Molecular Design Limited (GB) 2000-06-28 EP disclosed
EP-1009758-A1 META-BENZAMIDINE DERIVATIVES AS SERINE PROTEASE INHIBITORS Protherics Molecular Design Limited (GB) 2000-06-21 EP disclosed
EP-0490667-B1 HIV protease inhibitors JAPAN ENERGY CORP (JP) 1999-06-09 EP disclosed
WO-1999011658-A1 META-BENZAMIDINE DERIVATIVES AS SERIN PROTEASE INHIBITORS PROTEUS MOLECULAR DESIGN LTD. (GB) 1999-03-11 WO disclosed
WO-1999011657-A1 1-AMINO-7-ISOQUINOLINE DERIVATIVES AS SERINE PROTEASE INHIBITORS PROTEUS MOLECULAR DESIGN LTD. (GB) 1999-03-11 WO disclosed
US-5864045-A Heterocyclic substituted piperazinone derivatives HOECHST MARION ROUSSEL, INC. (US) 1999-01-26 US disclosed
US-5840726-A Heterocyclic substituted piperazinone derivatives HOECHST MARION ROUSSEL INC. (US) 1998-11-24 US disclosed
EP-0610943-A1 Pyridinium derivatives useful as PAF antagonists J. URIACH & CIA. S.A. (ES) 1994-08-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250092016-A1 COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CORONAVIRAL RELATED DISEASES ACE2, ACE, TMPRSS2 SMN1; SMN2 3396/4885MEN1 3749/4885KMT2A 3265/4885
US-20250084042-A1 Elagolix Sodium Compositions and Processes ELOVL5, ELOC, ELOVL3 SMN1; SMN2 2602/4885MEN1 1646/4885KMT2A 2023/4885
US-11840519-B2 Process for the synthesis of the sodium salt of 4-[[(1R)-2-[5-(2-fluoro-3-methoxyphenyl)-3-[[2-fluoro-6-(trifluoromethyl)-phenyl]methyl]-3,6-dihydro-4-methyl-2.6-dioxo-1(2H)-pyrimidinyl]-1-phenylethyl]amino]-butanoic acid (elagolix sodium salt) and intermediates of said process ELP1, BPNT1, EPX SMN1; SMN2 3833/4885MEN1 3852/4885KMT2A 886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.