Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5090319 | 0.84 | MEN1 (0.50) | SMN1; SMN2MEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL1624311 | 0.82 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9525952 | 0.82 | KDM4E (0.45) | SMN1; SMN2MEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL23120366 | 0.81 | SMN1; SMN2 (0.48) | SMN1; SMN2MEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5805153 | 0.80 | SMN1; SMN2 (0.49) | SMN1; SMN2MEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9363322 | 0.80 | TDP1 (0.49) | SMN1; SMN2MEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2798824 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2MEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9525162 | 0.78 | ALDH1A1 (0.51) | SMN1; SMN2F2GAALMNA | |
| SCHEMBL27572033 | 0.77 | TP53 (0.54) | SMN1; SMN2MEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9407535 | 0.76 | MEN1 (0.50) | SMN1; SMN2MEN1CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301751-B1 | PYRIDINIUM DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-4962113-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1990-10-09 | — | — | US | disclosed |
| EP-0301751-A1 | Pyridinium derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-02-01 | — | — | EP | disclosed |