Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | GAA | P10253 | 5/20 | 0.60 |
| ▸ | GLA | P06280 | 4/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | KDM5A | P29375 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 2/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700724 | 0.80 | KDM4E (0.66) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9525290 | 0.78 | KDM4E (0.64) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL7397061 | 0.78 | KDM4E (0.64) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9849406 | 0.78 | MAP4K4 (0.46) | KDM4EALDH1A1GAASCN2AKDM5A | |
| SCHEMBL11624684 | 0.77 | SCN2A (0.59) | KDM4EALDH1A1GAASCN2AKDM5A | |
| SCHEMBL4474609 | 0.77 | MDM2 (0.62) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL11735164 | 0.75 | KDM4E (0.64) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9526447 | 0.75 | GAA (1.00) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL11163920 | 0.75 | KDM4E (0.64) | KDM4EALDH1A1GAAHPGDKDM5A | |
| SCHEMBL9700710 | 0.75 | KDM4E (0.64) | KDM4EALDH1A1GAAGLAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550576-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |