Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | GAA | P10253 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526090 | 0.80 | KDM4E (0.74) | KDM4EGAAALDH1A1GLAL3MBTL1 | |
| SCHEMBL11736261 | 0.80 | KDM4E (0.60) | KDM4EGAAALDH1A1GLAL3MBTL1 | |
| SCHEMBL9700724 | 0.80 | KDM4E (0.66) | KDM4EGAAALDH1A1GLAL3MBTL1 | |
| SCHEMBL7397061 | 0.78 | KDM4E (0.64) | KDM4EGAAALDH1A1GLAL3MBTL1 | |
| SCHEMBL9525290 | 0.78 | KDM4E (0.64) | KDM4EGAAALDH1A1GLAL3MBTL1 | |
| SCHEMBL11740127 | 0.78 | KDM4E (0.57) | KDM4EGAAALDH1A1GLAL3MBTL1 | |
| SCHEMBL9700707 | 0.78 | KDM4E (0.71) | KDM4EGAAALDH1A1GLAL3MBTL1 | |
| SCHEMBL9701346 | 0.78 | KDM4E (0.64) | KDM4EGAAALDH1A1GLAL3MBTL1 | |
| SCHEMBL9526447 | 0.78 | GAA (1.00) | KDM4EGAAALDH1A1GLAL3MBTL1 | |
| SCHEMBL11735164 | 0.78 | KDM4E (0.64) | KDM4EGAAALDH1A1GLAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |