Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 2/20 | 0.33 |
| ▸ | KDM4A | O75164 | 2/20 | 0.33 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.33 |
| ▸ | KDM3B | Q7LBC6 | 2/20 | 0.33 |
| ▸ | HIF1AN | Q9NWT6 | 2/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.33 |
| ▸ | PTGES | O14684 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9525256 | 0.85 | GCGR (0.33) | MEN1KMT2A | |
| SCHEMBL9528232 | 0.78 | RARB (0.47) | KDM4EMEN1GAAKMT2AHSD17B10 | |
| SCHEMBL9525985 | 0.78 | PTGES (0.38) | GPR84KDM4EMEN1GAATSHR | |
| SCHEMBL9525973 | 0.78 | PTGES (0.38) | GPR84KDM4EMEN1GAATSHR | |
| SCHEMBL8916664 | 0.78 | KDM4E (0.31) | KDM4EMEN1GAATSHRHTT | |
| SCHEMBL8916677 | 0.78 | KDM4E (0.31) | KDM4EMEN1GAATSHRHTT | |
| SCHEMBL9506321 | 0.68 | ALDH1A1 (0.50) | KDM4ETSHRHTTHSD17B10L3MBTL1 | |
| SCHEMBL9506292 | 0.68 | ALDH1A1 (0.50) | KDM4ETSHRHTTHSD17B10L3MBTL1 | |
| SCHEMBL9506138 | 0.68 | ALDH1A1 (0.50) | KDM4ETSHRHTTHSD17B10L3MBTL1 | |
| SCHEMBL9510040 | 0.68 | ALDH1A1 (0.50) | KDM4ETSHRHTTHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0351746-B1 | Optically active 1,3-dioxolane derivatives containing a mesogene group in position 4, method for their preparation and their use as doping agents in liquid-crystal mixtures | HOECHST AG (DE) | 1993-12-29 | — | — | EP | disclosed |
| EP-0351746-A1 | Optically active 1,3-dioxolane derivatives containing a mesogene group in position 4, method for their preparation and their use as doping agents in liquid-crystal mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-01-24 | — | — | EP | disclosed |