Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.56 |
| ▸ | DRD3 | P35462 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.54 |
| ▸ | HTR3B | O95264 | 1/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.54 |
| ▸ | HTR3A | P46098 | 1/20 | 0.54 |
| ▸ | HTR6 | P50406 | 1/20 | 0.54 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.54 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL217093 | 0.81 | DRD2 (0.66) | DRD2DRD3CYP2C19HTR3EHTR3B | |
| SCHEMBL4794209 | 0.76 | DRD2 (0.69) | DRD2DRD3CYP2C19HTR3EHTR3B | |
| SCHEMBL4071575 | 0.76 | DRD2 (0.59) | DRD2DRD3CYP2C19HTR3EHTR3B | |
| SCHEMBL3165674 | 0.74 | DRD2 (0.72) | DRD2DRD3CYP2C19HTR3EHTR3B | |
| SCHEMBL29138522 | 0.74 | DRD2 (0.67) | DRD2DRD3CYP2C19HTR3EHTR3B | |
| SCHEMBL30407688 | 0.74 | DRD2 (0.72) | DRD2DRD3CYP2C19HTR3EHTR3B | |
| SCHEMBL30720573 | 0.74 | DRD2 (0.66) | DRD2DRD3CYP2C19HTR3EHTR3B | |
| SCHEMBL4065094 | 0.73 | DRD2 (0.56) | DRD2DRD3CYP2C19HTR3EHTR3B | |
| SCHEMBL7773425 | 0.73 | DRD2 (0.68) | DRD2DRD3CYP2C19HTR3EHTR3B | |
| SCHEMBL3174809 | 0.73 | DRD2 (0.70) | DRD2DRD3CYP2C19HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272478-B1 | GLYCYRRHETIC ACID DERIVATIVES AND USE THEREOF | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1993-01-20 | — | — | EP | claimed |
| EP-0272478-B1 | GLYCYRRHETIC ACID DERIVATIVES AND USE THEREOF | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1993-01-20 | — | — | EP | disclosed |