Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.66 |
| ▸ | DRD3 | P35462 | 3/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.64 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.64 |
| ▸ | HTR3B | O95264 | 1/20 | 0.64 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.64 |
| ▸ | HTR3A | P46098 | 1/20 | 0.64 |
| ▸ | HTR6 | P50406 | 1/20 | 0.64 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.64 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30407688 | 0.82 | DRD2 (0.72) | DRD2DRD3CYP2C19HTR3EHTR3B | |
| SCHEMBL3165674 | 0.82 | DRD2 (0.72) | DRD2DRD3CYP2C19HTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL26690632 | 0.81 | MAPT (0.71) | DRD2DRD3CYP2C19HTR3EHTR3B | |
| SCHEMBL3020451 | 0.81 | DRD2 (0.70) | DRD2DRD3CYP2C19HTR3EHTR3B | |
| SCHEMBL3174809 | 0.81 | DRD2 (0.70) | DRD2DRD3CYP2C19HTR3EHTR3B | |
| SCHEMBL219349 | 0.81 | ALDH1A1 (0.61) | DRD2DRD3MAPTALDH1A1L3MBTL1 | |
| SCHEMBL5812682 | 0.81 | ADRA1A (0.56) | ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL9526010 | 0.81 | DRD2 (0.56) | DRD2DRD3CYP2C19HTR3EHTR3B | |
| SCHEMBL327835 | 0.79 | DRD2 (1.00) | DRD2DRD3CYP2C19HTR3EHTR3B | |
| SCHEMBL1267564 | 0.79 | DRD2 (0.68) | DRD2DRD3CYP2C19HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 345 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946031-A | Substituted aromatic phenol derivatives of KNa1.1 channel inhibitors | 北京大学 | 2024-04-30 | — | — | CN | claimed |
| CN-117396465-A | Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same | 阿斯克里斯有限公司 | 2024-01-12 | — | — | CN | claimed |
| CN-110337293-A | Therapeutic compound | 新泽西鲁特格斯州立大学 | 2019-10-15 | — | — | CN | claimed |
| US-20190070149-A1 | PRIMARY AMINES AND DERIVATIVES THEREOF AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. | 2019-03-07 | — | — | US | claimed |
| US-9663464-B2 | Carbazole derivatives acting on 5-HT7 receptor | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2017-05-30 | — | — | US | claimed |
| US-20160244408-A1 | CARBAZOLE DERIVATIVES ACTING ON 5-HT7 RECEPTOR | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2016-08-25 | — | — | US | claimed |
| US-9328107-B2 | Primary amines and derivatives thereof as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto | ARENA PHARMACEUTICALS, INC. (US) | 2016-05-03 | — | — | US | claimed |
| US-20160009752-A1 | PREGNANE-OXIMINO-AMINOALKYLETHERS AND PROCESS FOR PREPARATION THEREOF, USEFUL AS ANTIDIABETIC AND ANTIDYSLIPIDEMIC AGENTS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-01-14 | — | — | US | claimed |
| US-20150197492-A1 | NOVEL INDENO[1,2-c]QUINOLIN-11-ONE DERIVATIVES, PREPARATION METHOD AND APPLICATION THEREOF | NATIONAL DEFENSE MEDICAL CENTER (TW) | 2015-07-16 | — | — | US | claimed |
| US-8981131-B2 | Tricyclic compounds for the treatment of inflammatory disorders | Piramal Enterprises Limited (IN) | 2015-03-17 | — | — | US | claimed |
| US-5403842-A | Adrenergic blocking and antiserotonine agents; urogenital disorders including spasms of the urethral tract and prostrate problems | RECORDATI S.A., CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1995-04-04 | — | — | US | claimed |
| EP-0611748-A1 | Propanolamine derivatives and their use as hypotensive or antiglaucoma agents | Senju Pharmaceutical Co., Ltd. (JP) | 1994-08-24 | — | — | EP | claimed |
| EP-0374054-B1 | INDANE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND INTERMEDIATES OBTAINED, THEIR USE AS MEDICINES, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1993-10-06 | — | — | EP | claimed |
| WO-1993017007-A1 | HETEROBICYCLIC COMPOUNDS | RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA S.P.A. (IT) | 1993-09-02 | — | — | WO | claimed |
| EP-0558245-A1 | Heterobicyclic compounds as antagogists of alpha-1 adrenergic and SHT1A receptors | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 1993-09-01 | — | — | EP | claimed |
| EP-0120770-B1 | 2-AMINOETHYL PYRIDINE OR PYRAZINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | RIOM LABORATOIRES- C.E.R.M. "R.L.-CERM" - (S.A.) (FR) | 1988-03-23 | — | — | EP | claimed |
| EP-0110781-B1 | SUBSTITUTED (AMINO-2-ETHYL)-6-BENZOXAZOLINONES, THEIR PREPARATION AND A PHARMACEUTICAL COMPOSITION CONTAINING THEM | RIOM LABORATOIRES- C.E.R.M. (Société Anonyme) (FR) | 1987-04-01 | — | — | EP | claimed |
| US-4556656-A | HYPOTENSIVE, ANTIPSYCHOTIC, DIABETIC, AND ANALGESIC AGENTS | THE UPJOHN COMPANY (US) | 1985-12-03 | — | — | US | claimed |
| EP-0120770-A1 | 2-Aminoethyl pyridine or pyrazine derivatives, their preparation and pharmaceutical compositions containing them | RIOM LABORATOIRES- C.E.R.M. "R.L.-CERM" - (S.A.) (FR) | 1984-10-03 | — | — | EP | claimed |
| EP-0049203-A1 | Benzoxazolinones substituted in the 6-position by an amino-alcohol or amino-ketone chain, their preparation and their therapeutic use | RIOM LABORATOIRES- C.E.R.M. (Société Anonyme) (FR) | 1982-04-07 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190070149-A1 | PRIMARY AMINES AND DERIVATIVES THEREOF AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | HTR5A, HTR2A, HTR1A | DRD2 114/4885DRD3 490/4885CYP2C19 141/4885 |
| US-20160009752-A1 | PREGNANE-OXIMINO-AMINOALKYLETHERS AND PROCESS FOR PREPARATION THEREOF, USEFUL AS ANTIDIABETIC AND ANTIDYSLIPIDEMIC AGENTS | CYP3A43, CYP11B1, CYP11B2 | DRD2 2197/4885DRD3 605/4885CYP2C19 64/4885 |
| US-20150197492-A1 | NOVEL INDENO[1,2-c]QUINOLIN-11-ONE DERIVATIVES, PREPARATION METHOD AND APPLICATION THEREOF | TOP1, TOP2A, TOP2B | DRD2 3616/4885DRD3 3271/4885CYP2C19 307/4885 |
| US-20160244408-A1 | CARBAZOLE DERIVATIVES ACTING ON 5-HT7 RECEPTOR | HTR7, HTR3A, HTR3B | DRD2 220/4885DRD3 182/4885CYP2C19 125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.