Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.55 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526349 | 0.92 | NPC1 (0.66) | SMN1; SMN2NOTUML3MBTL1NPC1RAB9A | |
| SCHEMBL5426108 | 0.84 | NOTUM (0.65) | SMN1; SMN2NOTUML3MBTL1NPC1RAB9A | |
| SCHEMBL3721043 | 0.82 | NOTUM (0.55) | SMN1; SMN2NOTUML3MBTL1NPC1RAB9A | |
| SCHEMBL27616400 | 0.81 | NPC1 (0.84) | SMN1; SMN2NOTUML3MBTL1NPC1RAB9A | |
| SCHEMBL10422954 | 0.80 | TSHR (0.69) | SMN1; SMN2NOTUML3MBTL1TSHRGAA | |
| SCHEMBL9208129 | 0.79 | NOTUM (0.57) | SMN1; SMN2NOTUML3MBTL1NPC1RAB9A | |
| SCHEMBL926908 | 0.78 | NOTUM (0.69) | SMN1; SMN2NOTUML3MBTL1TSHRGAA | |
| SCHEMBL30039812 | 0.78 | NOTUM (0.69) | SMN1; SMN2NOTUML3MBTL1TSHRGAA | |
| SCHEMBL30253474 | 0.78 | SMN1; SMN2 (0.68) | SMN1; SMN2NOTUMTSHRGAASIGMAR1 | |
| SCHEMBL3089154 | 0.78 | SMN1; SMN2 (0.68) | SMN1; SMN2NOTUMTSHRGAASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301751-B1 | PYRIDINIUM DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-4962113-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1990-10-09 | — | — | US | disclosed |
| EP-0301751-A1 | Pyridinium derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-02-01 | — | — | EP | disclosed |