Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.66 |
| ▸ | RAB9A | P51151 | 4/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526047 | 0.92 | SMN1; SMN2 (0.59) | NPC1RAB9AL3MBTL1TSHRNOTUM | |
| SCHEMBL299090 | 0.85 | NPC1 (0.66) | NPC1RAB9AL3MBTL1TSHRNOTUM | |
| SCHEMBL2116912 | 0.83 | NPC1 (0.71) | NPC1RAB9AL3MBTL1TSHRNOTUM | |
| SCHEMBL29554766 | 0.83 | NPC1 (0.71) | NPC1RAB9AL3MBTL1TSHRNOTUM | |
| SCHEMBL27882103 | 0.83 | NPC1 (0.71) | NPC1RAB9AL3MBTL1TSHRNOTUM | |
| SCHEMBL5797625 | 0.83 | RAB9A (0.63) | NPC1RAB9AL3MBTL1TSHRNOTUM | |
| SCHEMBL3662555 | 0.81 | NPC1 (0.60) | NPC1RAB9AL3MBTL1TSHRNOTUM | |
| Hydrochloric Acid SCHEMBL7423344 | 0.80 | NPC1 (0.59) | NPC1RAB9AL3MBTL1TSHRNOTUM | |
| SCHEMBL7469639 | 0.79 | NPC1 (1.00) | NPC1RAB9AL3MBTL1TSHRNOTUM | |
| SCHEMBL30681385 | 0.79 | RAB9A (0.66) | NPC1RAB9AL3MBTL1TSHRNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301751-B1 | PYRIDINIUM DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-4962113-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1990-10-09 | — | — | US | disclosed |
| EP-0301751-A1 | Pyridinium derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-02-01 | — | — | EP | disclosed |