Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.97 |
| ▸ | MEN1 | O00255 | 2/20 | 0.97 |
| ▸ | HTT | P42858 | 2/20 | 0.97 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.97 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.97 |
| ▸ | EGFR | P00533 | 1/20 | 0.97 |
| ▸ | LMNA | P02545 | 1/20 | 0.97 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.97 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.97 |
| ▸ | LCK | P06239 | 1/20 | 0.97 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.97 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.97 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.97 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.97 |
| ▸ | HSPD1 | P10809 | 3/20 | 0.77 |
| ▸ | HSPE1 | P61604 | 3/20 | 0.77 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.59 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tribromsalan SCHEMBL121315 | 0.98 | MEN1 (1.00) | MAPTMEN1HTTKMT2AALDH1A1 | |
| Tribromsalan SCHEMBL29392740 | 0.98 | MEN1 (1.00) | MAPTMEN1HTTKMT2AALDH1A1 | |
| Tribromsalan SCHEMBL11242287 | 0.91 | MAPT (0.86) | MAPTMEN1HTTKMT2AALDH1A1 | |
| SCHEMBL11679716 | 0.88 | KMT2A (0.80) | MAPTMEN1HTTKMT2AALDH1A1 | |
| Tribromsalan SCHEMBL28197429 | 0.87 | MEN1 (0.79) | MAPTMEN1HTTKMT2AALDH1A1 | |
| Tribromsalan SCHEMBL29381849 | 0.87 | MAPT (0.79) | MAPTMEN1HTTKMT2AALDH1A1 | |
| Tribromsalan SCHEMBL28310130 | 0.87 | MEN1 (0.79) | MAPTMEN1HTTKMT2AALDH1A1 | |
| Metabromsalan SCHEMBL1162534 | 0.87 | HSPD1 (1.00) | MAPTMEN1HTTKMT2AALDH1A1 | |
| Metabromsalan SCHEMBL29350968 | 0.87 | HSPD1 (1.00) | MAPTMEN1HTTKMT2AALDH1A1 | |
| Tribromsalan SCHEMBL28197430 | 0.86 | HSPD1 (0.80) | MAPTMEN1HTTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0162574-B1 | ORAL HYGIENE COMPOSITIONS | JOHNSON & JOHNSON (US) | 1993-03-24 | — | — | EP | disclosed |
| US-4568540-A | FLUORIDE SALT, ZINC SALT, BUFFERING AGENT AND VEHICLE | JOHNSON & JOHNSON (US) | 1986-02-04 | — | — | US | disclosed |
| EP-0162574-A2 | Oral hygiene compositions | JOHNSON & JOHNSON (US) | 1985-11-27 | — | — | EP | disclosed |
| US-4022880-A | ZINC IONS, 3,4,5-TRIBROMO-SALICYLANILIDE, QUATERNARY AMMONIUM COMPOUNDS | LEVER BROTHERS COMPANY (US) | 1977-05-10 | — | — | US | disclosed |